[3:39 PM] Rifki Akbar
C1778
Sigma-Aldrich

CAFFEINE

Empform:

C8H10N4O2

Synonyms English:

1,3,7-Trimethylxanthine

Nacres: NA.21
Mdl No: MFCD00005758
Fw: 194.19
Pubchem Substance Id: 24892436
Grouped product items
SKU Pack Size Availability Price Quantity
C1778-1VL 1vial Available to ship on April 25, 2024
IDR 2,621,000.00
C1778-5VL - Available to ship on April 25, 2024
IDR 10,465,000.00
Request a Bulk Order Check Availability

Properties

Properties
form crystalline
gene information human ... ADORA1(134) ADORA2A(135) ADORA2B(136) ADORA3(140) PDE4B(5142)
mouse ... Adora2b(11541)
rat ... Adora1(29290) Adora2a(25369)
grade Sigma Reference Standard
inchi 1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H1-3H3
inchi key RYYVLZVUVIJVGH-UHFFFAOYSA-N
MDM Code C1778-1VL
Material Number C1778
Business Unit 777
Shipping Mode AIR
MRP Type PD
Local HS Code 29393000
Legacy SIGMA
Plant 6311
Sales Org 6304

Description

Biochem/physiol Actions

A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1778.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

Supplied in amber screw-cap vials

SAFETY INFORMATION

Signal Word

Warning

P264 - P270 - P301 + P312 - P501

RIDADRRIDADR

WGK Germany

WGK 1

Flash Point (F)

Flash Point (C)

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

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