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    • CAFFEINE

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    Documents SDS COO/COA Specification Sheet
    C1778
    Sigma-Aldrich

    CAFFEINE

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    Empform:

    C8H10N4O2

    Synonyms English:

    1,3,7-Trimethylxanthine

    Nacres: NA.21
    Mdl No: MFCD00005758
    Fw: 194.19
    Pubchem Substance Id: 24892436
    Grouped product items
    SKU Pack Size Availability Price Quantity
    C1778-1VL 1vial Available to ship on January 07, 2024
    IDR 2,621,000.00
    C1778-5VL - Available to ship on January 07, 2024
    IDR 10,465,000.00
    Request a Bulk Order Check Availability
    Documents SDS COO/COA Specification Sheet

    Properties

    Properties
    form crystalline
    gene information human ... ADORA1(134) ADORA2A(135) ADORA2B(136) ADORA3(140) PDE4B(5142)
    mouse ... Adora2b(11541)
    rat ... Adora1(29290) Adora2a(25369)
    grade Sigma Reference Standard
    inchi 1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H1-3H3
    inchi key RYYVLZVUVIJVGH-UHFFFAOYSA-N
    MDM Code C1778-1VL
    Material Number C1778
    Business Unit 777
    Shipping Mode AIR
    MRP Type PD
    Local HS Code 29393000
    Legacy SIGMA
    Plant 6311
    Sales Org 6304

    Description

    Biochem/physiol Actions

    A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.

    Other Notes

    Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1778.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

    Packaging

    Supplied in amber screw-cap vials

    SAFETY INFORMATION

    GHS07

    Signal Word

    Warning

    H302

    P264 - P270 - P301 + P312 - P501

    RIDADRRIDADR

    WGK Germany

    WGK 1

    Flash Point (F)

    Flash Point (C)

    Target Organs

    Risk Statement

    Supplemental Hazard Statements

    DOCUMENTATION

    Certificate of Analysis View Sample COA
    Lot Number
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    Certificate of Origin
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