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    • CHLOROTHIAZIDE

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    Documents SDS COO/COA Specification Sheet
    C4911
    Sigma-Aldrich

    CHLOROTHIAZIDE

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    Empform:

    C7H6ClN3O4S2

    Synonyms English:

    6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

    Nacres: NA.77
    Mdl No: MFCD00058576
    Fw: 295.72
    Pubchem Substance Id: 24278150
    CAS Number: 58-94-6
    Grouped product items
    SKU Pack Size Availability Price Quantity
    C4911-50G - Available to ship on June 25, 2023
    IDR4,941,000.00
    Request a Bulk Order Check Availability
    Documents SDS COO/COA Specification Sheet

    Properties

    Properties
    assay ≥
    assay range 98% (HPLC)
    blade diam. synthetic (organic)
    Description CHLOROTHIAZIDE
    format powder
    glass tube l × o.d. × i.d. human ... CA1(759) CA4(762) SLC12A3(6559)
    inchi key 1S/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(912)13)17(1415)11-3-10-5/h1-3H(H1011)(H291213)
    indiff. to chromic acid JBMKAUGHUNFTOL-UHFFFAOYSA-N
    MDM Code C4911-50G
    Material Number C4911
    Business Unit 760
    Shipping Mode AIR
    MRP Type YP
    Local HS Code 29359000
    Legacy SIGMA
    Plant 6311
    Sales Org 6304
    CAS Number 58-94-6

    Description

    Application

    Chlorothiazide has been used as a reference standard in parallel artificial membrane permeability assay (PAMPA). It has also been used to test its effect on blocking pendrin activity.

    Biochem/physiol Actions

    Chlorothiazide (CTLD) shows structural resemblance with hydrochlorothiazide by having a sulfonamide group, but exhibits a long action duration. CTLD is an inhibitor of carbonic anhydrase and is more potent than hydrochlorothiazide.

    General description

    Chlorothiazide (CTLD) is a thiazide-like diuretics 

    Immunogen

    and has antihypertensive effects.

    SAFETY INFORMATION

    GHS08

    Signal Word

    Danger

    H317 - H334

    P261 - P272 - P280 - P284 - P302 + P352 - P304 + P340 + P312

    RIDADRRIDADR

    WGK Germany

    WGK 2

    Flash Point (F)

    Not applicable

    Flash Point (C)

    Not applicable

    Target Organs

    Risk Statement

    Supplemental Hazard Statements

    DOCUMENTATION

    Certificate of Analysis View Sample COA
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    Certificate of Origin
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