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    • DL-Dithiothreitol

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    Documents SDS COO/COA Specification Sheet
    D5545
    Sigma-Aldrich

    DL-Dithiothreitol

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    Linear Formula:

    HSCH2CH(OH)CH(OH)CH2SH

    Empform:

    C4H10O2S2

    Synonyms English:

    threo-1,4-Dimercapto-2,3-butanediol; Cleland’s reagent; DTT

    Nacres: NA.21
    Mdl No: MFCD00004877
    Fw: 154.25
    Pubchem Substance Id: 24893941
    Grouped product items
    SKU Pack Size Availability Price Quantity
    D5545-5G 5G Available to ship on October 21, 2023
    IDR6,001,000.00
    D5545-1G - Available to ship on October 21, 2023
    IDR1,838,000.00
    D5545-25G - Available to ship on October 21, 2023
    IDR22,115,000.00
    Request a Bulk Order Check Availability
    Documents SDS COO/COA Specification Sheet

    Properties

    Properties
    Description DL-Dithiothreitol BioXtra, >=99.0% (titration)
    MDM Code D5545-5G
    Material Number D5545
    Business Unit 499
    Shipping Mode AIR
    MRP Type PD
    Local HS Code 29309090
    Legacy SIGMA
    Plant 6311
    Sales Org 6304

    Description

    Application

    An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol. Typically, a seven fold lower concentration of DTT (100 mM) is needed than is used for 2-mercaptoethanol (5% v/v, 700 mM).

    SAFETY INFORMATION

    GHS05,GHS07

    Signal Word

    Danger

    H302 - H315 - H318

    P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

    RIDADRRIDADR

    WGK Germany

    WGK 3

    Flash Point (F)

    Not applicable

    Flash Point (C)

    Not applicable

    Target Organs

    Risk Statement

    Supplemental Hazard Statements

    DOCUMENTATION

    Certificate of Analysis View Sample COA
    Lot Number
    How to enter Lot Number (COA)
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    Certificate of Origin
    Lot Number
    How to enter Lot Number (COA)
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