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Dimethyl sulfoxide

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Documents SDS COO/COA Specification Sheet

D8418

Sigma-Aldrich

Dimethyl sulfoxide

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Linear Formula:

(CH₃)₂SO

Empform:

C₂H₆OS

Synonyms English:

Methyl Sulfoxide

Nacres: NA.52

Mdl No: MFCD00002089

Fw: 78.13

Pubchem Substance Id: 24894214

CAS Number: 67-68-5

Grouped product items
SKU	Pack Size	Availability	Price
D8418-100ML	1X100mL	Available to ship on October 21, 2023	IDR1,385,000.00	Add to Favorite List
D8418-500ML	500ML	Available to ship on October 21, 2023	IDR4,055,000.00	Add to Favorite List
D8418-50ML	50ML	Available to ship on October 21, 2023	IDR812,000.00	Add to Favorite List
D8418-250ML	250ML	Available to ship on October 21, 2023	IDR2,740,000.00	Add to Favorite List
D8418-1L	-	Available to ship on October 21, 2023	IDR5,882,000.00	Add to Favorite List
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Documents SDS COO/COA Specification Sheet

Properties

Properties
Description	Dimethyl sulfoxide for molecular biology
MDM Code	D8418-500ML
Material Number	D8418
Business Unit	042
Shipping Mode	AIR
MRP Type	PD
Local HS Code	29309090
Legacy	SIGMA
Plant	6311
Sales Org	6304
CAS Number	67-68-5

Description

Application

DMSO (dimethyl sulfoxide) is a highly polar, aprotic organic solvent with many applications in organic chemistry and molecular biology. DMSO is routinely used in

polymerase chain reaction (PCR)
amplification of cDNA libraries
DNA sequencing
column-loading buffers for poly(A)+ RNA selection
buffers for the transformation of competent E. coli
transfection protocols.

Dimethyl sulfoxide has been used-

as an oligonucleotide solvent in array spotting[1]
as a solvent during miRNA microarray analysis and quantitative real-time PCR (qRT-PCR)
for cell lysis during MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay
for the preparation of the stock solution during MMP (mitochondrial membrane potential)cytofluorimetric assessment
in the storage of human and animal cell lines and bacteriophage λ as a cryoprotective agent.

To prepare a sterile filtered DMSO solution, it is recommended to use a PTFE or nylon membrane. Cellulose acetate membranes are not recommended.

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Features and Benefits

This product is free from DNases, RNases, phosphatases and proteases.

General description

Features and Benefits:

Suitable for Molecular Applications
Nuclease-Free DMSO
DNase-Free, RNase-Free, Protease-Free, Phosphatase-Free
Molecular Biology Grade DMSO

Dimethyl sulfoxide (DMSO) is a highly polar organic reagent that has exceptional solvent properties for organic and inorganic chemicals.
This product is designated as Molecular Biology grade and is suitable for molecular biology applications. It has been analyzed for the presence of nucleases and proteases.

SAFETY INFORMATION

Pictograms

Signal Word

Hazard Statements

Precautionary Statements

RIDADRRIDADR

WGK Germany

WGK 1

Flash Point (F)

188.6 °F - closed cup

Flash Point (C)

87 °C - closed cup

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA

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Certificate of Origin

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