Search
Advanced Search
ID
ENGLISH
Language
CHANGE LANGUAGE
Menu
Location
ID
Language
ENGLISH
Language
CHANGE LANGUAGE
Account
Cart 0
    • Compare ()
  • Quick Order
    • Erythromycin, meets USP testing specific

    All Photos (4)

    Documents SDS COO/COA Specification Sheet
    E0774
    Sigma-Aldrich

    Erythromycin, meets USP testing specific

    Write a review

    Empform:

    C37H67NO13

    Nacres: NA.76
    Mdl No: MFCD00084654
    Fw: 733.93
    Pubchem Substance Id: 24894374
    CAS Number: 114-07-8
    Grouped product items
    SKU Pack Size Availability Price Quantity
    E0774-5G - Available to ship on October 21, 2023
    IDR2,297,000.00
    E0774-100G - Available to ship on October 21, 2023
    IDR21,832,000.00
    E0774-25G - Available to ship on October 21, 2023
    IDR9,156,000.00
    Request a Bulk Order Check Availability
    Documents SDS COO/COA Specification Sheet

    Properties

    Properties
    agency USP/NF
    antibiotic activity spectrum Gram-negative bacteria
    applications pharmaceutical (small molecule)
    Description Erythromycin, meets USP testing specific
    form solid
    gene information human ... ABCB1(5243) CYP3A4(1576) MLNR(2862)
    mouse ... Abcb1a(18671) Abcb1b(18669)
    inchi 1S/C37H67NO13/c1-14-25-37(1045)30(41)20(4)27(39)18(2)16-35(844)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(946-13)31(42)23(7)48-26/h18-2628-323440-4244-45H14-17H21-13H3/t18-19-20+21+22-23+24+25-26+28-29+30-31+32-34+35-36-37-/m1/s1
    inchi key ULGZDMOVFRHVEP-RWJQBGPGSA-N
    MDM Code E0774-5G
    Material Number E0774
    Business Unit 777
    Shipping Mode AIR
    MRP Type YP
    Local HS Code 29415000
    Legacy SIGMA
    Plant 6311
    Sales Org 6304
    CAS Number 114-07-8

    Description

    Application

    Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.

    Biochem/physiol Actions

    Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex.

    Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.

    Caution

    This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C.

    General description

    Chemical structure: macrolide

    Preparation Note

    This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.

    SAFETY INFORMATION

    Signal Word

    RIDADRRIDADR

    WGK Germany

    WGK 3

    Flash Point (F)

    Not applicable

    Flash Point (C)

    Not applicable

    Target Organs

    Risk Statement

    Supplemental Hazard Statements

    DOCUMENTATION

    Certificate of Analysis View Sample COA
    Lot Number
    How to enter Lot Number (COA)
    Search
    Certificate of Origin
    Lot Number
    How to enter Lot Number (COA)
    Search

    More Documents

    TECHNICAL SERVICE

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.