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    • Ethylenediaminetetraacetic acid disodium salt dihydrate

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    Documents SDS COO/COA Specification Sheet
    ED2SS
    Sigma-Aldrich

    Ethylenediaminetetraacetic acid disodium salt dihydrate

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    Empform:

    C10H14N2Na2O8 · 2H2O

    Synonyms English:

    Disodium ethylenediaminetetraacetate dihydrate

    Nacres: NA.77
    Fw: 372.24
    Pubchem Substance Id: 24894708
    CAS Number: 6381-92-6
    Grouped product items
    SKU Pack Size Availability Price Quantity
    ED2SS-5KG 5KG Available to ship on December 30, 2023
    IDR 17,533,000.00
    ED2SS-1KG 1KG Available to ship on December 30, 2023
    IDR 4,765,000.00
    ED2SS-100G - Available to ship on December 30, 2023
    IDR 1,445,000.00
    ED2SS-2.5KG - Available to ship on December 30, 2023
    IDR 9,958,000.00
    ED2SS-250G - Available to ship on December 30, 2023
    IDR 2,724,000.00
    ED2SS-500G - Available to ship on December 30, 2023
    IDR 3,503,000.00
    ED2SS-50G - Available to ship on December 30, 2023
    IDR 847,000.00
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    Documents SDS COO/COA Specification Sheet

    Properties

    Properties
    assay 98.5-101.5% (titration)
    biological source synthetic (organic)
    Description Ethylenediaminetetraacetic acid disodium salt dihydrate reagent grade, 98.5-101.5% (titration)
    form powder
    grade reagent grade
    inchi 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20
    inlet and outlet diam. /h1-6H2(H1314)(H1516)(H1718)(H1920)
    inlet cga 2*1H2/q
    inlet connection diam. 2*+1
    inlet diam. /p-2
    inlet i.d. OVBJJZOQPCKUOR-UHFFFAOYSA-L
    MDM Code ED2SS-5KG
    Material Number ED2SS
    Business Unit 499
    Shipping Mode AIR
    MRP Type PD
    Local HS Code 29224900
    Legacy SIGMA
    Plant 6311
    Sales Org 6304
    CAS Number 6381-92-6

    Description

    Application

    Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

    Biochem/physiol Actions

    Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases.

    General description

    Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions to form an octahedral complex especially with cations. Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests. It enhances the antibacterial activity of lysozyme. EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease. EDTA chelation therapy protects from lipid peroxidation events in liver fibrosis.

    SAFETY INFORMATION

    GHS07,GHS08

    Signal Word

    Warning

    H332 - H373 - H412

    P260 - P271 - P273 - P304 + P340 + P312 - P314 - P501

    RIDADRRIDADR

    WGK Germany

    WGK 2

    Flash Point (F)

    Not applicable

    Flash Point (C)

    Not applicable

    Target Organs

    Respiratory Tract

    Risk Statement

    Supplemental Hazard Statements

    DOCUMENTATION

    Certificate of Analysis View Sample COA
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    Certificate of Origin
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