G1264
Sigma-Aldrich

GENTAMICIN SULFATE SALT BIOREAGENT, SUI&

Synonyms English:

Gentiomycin C

Nacres: NA.76
Mdl No: MFCD00270181
Pubchem Substance Id: 329799833
Grouped product items
SKU Pack Size Availability Price Quantity
G1264-1G - Available to ship on March 25, 2024
IDR 3,539,000.00
G1264-100G - Available to ship on March 25, 2024
IDR 148,602,000.00
G1264-250MG - Available to ship on March 25, 2024
IDR 1,322,000.00
G1264-50MG - Available to ship on March 25, 2024
IDR 630,000.00
G1264-5G - Available to ship on March 25, 2024
IDR 11,873,000.00
Request a Bulk Order Check Availability

Properties

Properties
antibiotic activity spectrum Gram-negative bacteria
biological source Micromonospora purpurea
components Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiring five equivalents of sulfuric acid per mole of gentamicin base.
Description GENTAMICIN SULFATE SALT BIOREAGENT, SUI&
form powder
inchi 1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(229)8-30-20
inchi key 1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(228)7-29-19
indiff. to chromic acid 1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17
inherent viscosity 1-5(23)4/h9-2025-29H5-822-24H21-4H3
inlet and outlet diam. 8-1925-28H4-721-24H21-3H3
inlet and outlet nptm × nptm 8-1824-27H3-720-23H21-2H3
inlet and outlet size (H21234)/t9-10-11+12-13+14+15-16-17+18-19-20-21+
inlet cga 8-9-10+11-12+13+14-15-16+17-18-19-20+
inlet connection diam. 8-9+10-11+12-13+14+15-16+17+18+19-
inlet connection size /m110./s1
inlet diam. RDEIXVOBVLKYNT-HDZPSJEVSA-N
MDM Code G1264-1G
Material Number G1264
Business Unit 694
Shipping Mode AIR
MRP Type YP
Local HS Code 29419000
Legacy SIGMA
Plant 6311
Sales Org 6304

Description

Analysis Note

Solubility- freely soluble in water, practically insoluble in ethanol

Application

Gentamicin sulfate, a broad-spectrum antibiotic, has been used as a selection agent (gentamicin-resistance gene) in cell culture and molecular biology applications. This product is recommended for use at 50 mg/L.

Biochem/physiol Actions

Mode of action: Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface.

Antimicrobial spectrum: Includes Gram-negative and Gram-positive bacteria, including strains resistant to tetracycline, chloramphenicol, kanamycin and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus and Streptococcus.

Caution

Sterile solutions should be stored at 2-8°C. Solutions have also been shown to be stable at room temperature and in boiling aqueous buffers of pH 2-142.

General description

Chemical structure: aminoglycoside

SAFETY INFORMATION

Signal Word

Warning

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

RIDADRRIDADR

WGK Germany

WGK 2

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

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