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    • Imidazole

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    Documents SDS COO/COA Specification Sheet
    I5513
    Sigma-Aldrich

    Imidazole

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    Empform:

    C3H4N2

    Synonyms English:

    1,3-Diaza-2,4-cyclopentadiene; Glyoxaline

    Nacres: NA.25
    Mdl No: MFCD00005183
    Fw: 68.08
    Pubchem Substance Id: 24896072
    Grouped product items
    SKU Pack Size Availability Price Quantity
    I5513-5G 5G Available to ship on June 29, 2023
    IDR1,142,000.00
    I5513-100G 100G Available to ship on June 29, 2023
    IDR10,898,000.00
    I5513-25G 25G Available to ship on June 29, 2023
    IDR3,633,000.00
    Request a Bulk Order Check Availability
    Documents SDS COO/COA Specification Sheet

    Properties

    Properties
    applications diagnostic assay manufacturing
    assay ≥
    assay range 99% (titration)
    bromine number 256 
    brush size diam. × l ?C (lit.)
    Description Imidazole for molecular biology, >=99% (titration)
    format DNase RNase and protease none detected
    fragrance allergen crystalline powder
    graduations and accuracy measuring range for molecular biology
    indiff. to chromic acid 1S/C3H4N2/c1-2-5-3-4-1/h1-3H(H45)
    inherent viscosity RAXXELZNTBOGNW-UHFFFAOYSA-N
    MDM Code I5513-5G
    Material Number I5513
    Business Unit 499
    Shipping Mode AIR
    MRP Type PD
    Local HS Code 29332900
    Legacy SIGMA
    Plant 6311
    Sales Org 6304

    Description

    Application

    Excellent for buffers in the range of pH 6.2-7.8

    Biochem/physiol Actions

    Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).

    General description

    Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.

    SAFETY INFORMATION

    GHS05,GHS07,GHS08

    Signal Word

    Danger

    H302 - H314 - H360D

    P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

    RIDADRRIDADR

    WGK Germany

    WGK 2

    Flash Point (F)

    293.0 °F - closed cup

    Flash Point (C)

    145 °C - closed cup

    Target Organs

    Risk Statement

    Supplemental Hazard Statements

    DOCUMENTATION

    Certificate of Analysis View Sample COA
    Lot Number
    How to enter Lot Number (COA)
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    Certificate of Origin
    Lot Number
    How to enter Lot Number (COA)
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