I5513
Sigma-Aldrich

Imidazole

Empform:

C3H4N2

Synonyms English:

1,3-Diaza-2,4-cyclopentadiene; Glyoxaline

Nacres: NA.25
Mdl No: MFCD00005183
Fw: 68.08
Pubchem Substance Id: 24896072
Grouped product items
SKU Pack Size Availability Price Quantity
I5513-5G 5G Available to ship on June 29, 2023
IDR1,142,000.00
I5513-100G 100G Available to ship on June 29, 2023
IDR10,898,000.00
I5513-25G 25G Available to ship on June 29, 2023
IDR3,633,000.00
Request a Bulk Order Check Availability

Properties

Properties
applications diagnostic assay manufacturing
assay
assay range 99% (titration)
bromine number 256 
brush size diam. × l ?C (lit.)
Description Imidazole for molecular biology, >=99% (titration)
format DNase RNase and protease none detected
fragrance allergen crystalline powder
graduations and accuracy measuring range for molecular biology
indiff. to chromic acid 1S/C3H4N2/c1-2-5-3-4-1/h1-3H(H45)
inherent viscosity RAXXELZNTBOGNW-UHFFFAOYSA-N
MDM Code I5513-5G
Material Number I5513
Business Unit 499
Shipping Mode AIR
MRP Type PD
Local HS Code 29332900
Legacy SIGMA
Plant 6311
Sales Org 6304

Description

Application

Excellent for buffers in the range of pH 6.2-7.8

Biochem/physiol Actions

Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).

General description

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.

SAFETY INFORMATION

GHS05,GHS07,GHS08

Signal Word

Danger

H302 - H314 - H360D

P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

RIDADRRIDADR

WGK Germany

WGK 2

Flash Point (F)

293.0 °F - closed cup

Flash Point (C)

145 °C - closed cup

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

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