Beta-Lactamase Inhibitor Screening Kit Sufficient for 100 Colorimetric tests
detection method
colorimetric
MDM Code
MAK222-1KT
Material Number
MAK222
Business Unit
777
Shipping Mode
COU
MRP Type
PD
Local HS Code
38229090
Legacy
SIGMA
Plant
6311
Sales Org
6304
Description
Application
Beta-Lactamase Inhibitor Screening Kit has been used in enzymatic assays.
Features and Benefits
Compatible with high-throughput handling systems.
General description
β-Lactamase (β-lactamase, βL, EC 3.5.2.6) is an enzyme first identified in Escherichia coli and has been described as penicillinase. A number of βLs have since been identified from various bacteria. β-Lactamases specifically hydrolyze β-lactam rings present in antibiotics such as penicillin, cephalosporins, monobactam, and carbapenem, and confer resistance against these antibiotics.
Principle
The β-Lactamase Inhibitor Screening Kit is a rapid, simple and sensitive assay that is suitable for high throughput screening of β-Lactamase inhibitors. βL activity is measured by hydrolyzing a chromogenic cephalosporin called nitrocefin, producing a colorimetric product (A490), proportional to the enzymatic activity present.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.