[3:39 PM] Rifki Akbar
RAB0711
Sigma-Aldrich

Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit

Grouped product items
SKU Pack Size Availability Price Quantity
RAB0711-1KT 1KIT Available to ship on May 18, 2024
IDR 12,553,000.00
Request a Bulk Order Check Availability

Properties

Properties
assay range inter-assay cv: <
astm d 2162 10%
intra-assay cv: <
astm d 301-56 12%
Description Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit
determination of p-n colorimetric
glass tube o.d. × l human ... CSF1R(1436)
MDM Code RAB0711-1KT
Material Number RAB0711
Business Unit 759
Shipping Mode AIR
MRP Type PD
Local HS Code 30021500
Legacy SIGMA
Plant 6311
Sales Org 6304
CAS Number 0

Description

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

CSF1R (colony stimulating factor 1 receptor) acts as a receptor for CSF1 and regulates monocyte and macrophage functioning. The protein and its ligand are linked to poor prognosis in patients with solid tumors and in patients with female reproductive cancers. In breast cancers, with decreased claudin levels, this protein regulates the switch between proliferative and invasive state of the tumor, acting downstream of TGFβ (tumor growth factor β). Haploinsufficiency in this receptor might lead to aberration of microglial function, which might be a contributor to the pathogenesis of hereditary diffuse leukoencephalopathy with spheroids (HDLS).

General description

CSF1R (colony stimulating factor 1 receptor) is a member of the platelet-derived growth factor (PDGF) family of proteins and is a type III RTK (receptor tyrosine kinase). CSF1R is composed of five immunoglobulin (Ig)-like domains, a transmembrane region, a juxtamembrane domain and kinase insert domain (KID) intersecting the kinase domain.

SAFETY INFORMATION

Signal Word

Warning

RIDADRRIDADR

WGK Germany

WGK 3

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.