sample type serum sample type cell culture supernatant(s) sample type plasma
MDM Code
RAB0750-1KT
Material Number
RAB0750
Business Unit
759
Shipping Mode
AIR
MRP Type
PD
Local HS Code
30021500
Legacy
SIGMA
Plant
6311
Sales Org
6304
CAS Number
0
Description
Application
For research use only. Not for use in diagnostic procedures. Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Plasminogen activator, urokinase receptor (PLAUR) is implicated in tumor invasion, angiogenesis and metastasis. It acts as a key regulator of cell-surface plasminogen activator. It is involved in various normal and pathological processes. Overexpression of the gene has been observed in various types of cancers, including head and neck squamous cell carcinoma (HNSCC). Thus, it is considered as an potent biomarker for targeted imaging or therapy. Elevated expression of PLAUR leads to the progression of kidney disease in children.
General description
The antibody pair provided in this kit recognizes human Urokinase Plasminogen Activator Surface Receptor.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word samplein the text box provided for lot number.
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