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    • STREPTOMYCIN SULFATE

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    Documents SDS COO/COA Specification Sheet
    S6501
    Sigma-Aldrich

    STREPTOMYCIN SULFATE

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    Linear Formula:

    C21H39N7O12 · 1.5 H2SO4

    Empform:

    C21H39N7O12 · 1.5H2O4S

    Nacres: NA.76
    Mdl No: MFCD00037023
    Fw: 728.69
    Pubchem Substance Id: 24899705
    Grouped product items
    SKU Pack Size Availability Price Quantity
    S6501-5G - Available to ship on October 28, 2023
    IDR2,023.00
    S6501-100G - Available to ship on October 21, 2023
    IDR2,039,000.00
    S6501-1KG - Available to ship on October 21, 2023
    IDR15,150,000.00
    S6501-50G - Available to ship on October 21, 2023
    IDR1,364,000.00
    S6501-25G - Available to ship on October 28, 2023
    IDR1,750.00
    Request a Bulk Order Check Availability
    Documents SDS COO/COA Specification Sheet

    Properties

    Properties
    antibiotic activity spectrum Gram-negative bacteria
    biological source Streptomyces griseus
    Description STREPTOMYCIN SULFATE
    form powder
    inchi 1S/2C21H39N7O12.3H2O4S/c2*1-5-21(364-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35
    inchi key 3*1-5(23)4/h2*4-18262931-36H3H21-2H3(H4222327)(H4242528)
    indiff. to chromic acid 3*(H21234)/t2*5-6-7-8+9-10-11-12+13-14-15-16-17-18-21+
    inlet and outlet nptm × nptm /m00.../s1
    inlet and outlet size QTENRWWVYAAPBI-YZTFXSNBSA-N
    MDM Code S6501-5G
    Material Number S6501
    Business Unit 777
    Shipping Mode AIR
    MRP Type PD
    Local HS Code 29412000
    Legacy SIGMA
    Shelf Life 61
    Plant 6311
    Sales Org 6304

    Description

    Application

    Streptomycin is used to study mechanisms of streptomycin resistance and is often used together with penicillin and other agents to inhibit bacterial contamination in cell culture applications. It is recommended for use in molecular biology applications at 25-50μg/mL, in cell culture applications at 100 mg/L and in embryo culture at 50 mg/L.

    Biochem/physiol Actions

    Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.

    Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.

    Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.

    Caution

    Solutions can be stored at 2-8°C for up to a month or at -20°C for more extended periods. At 37°C, solutions are stable for three days.

    General description

    Chemical structure: aminoglycoside

    Other Notes

    Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place

    Preparation Note

    Stock solutions should be prepared directly in the vial with sterile water at concentrations between 20-25 mg/mL.

    SAFETY INFORMATION

    GHS07,GHS08

    Signal Word

    Warning

    H302 - H361fd

    P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313

    RIDADRRIDADR

    WGK Germany

    WGK 3

    Flash Point (F)

    Not applicable

    Flash Point (C)

    Not applicable

    Target Organs

    Risk Statement

    Supplemental Hazard Statements

    DOCUMENTATION

    Certificate of Analysis View Sample COA
    Lot Number
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    Certificate of Origin
    Lot Number
    How to enter Lot Number (COA)
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