[3:39 PM] Rifki Akbar
SAB4500003
Sigma-Aldrich

ANTI-BCL-2

Synonyms English:

Apoptosis regulator Bcl-2

Nacres: NA.41
Mdl No: MFCD00239644
Grouped product items
SKU Pack Size Availability Price Quantity
SAB4500003-100UG - Available to ship on May 18, 2024
IDR 7,025,000.00
Request a Bulk Order Check Availability

Properties

Properties
antibody form affinity isolated antibody
antibody product type primary antibodies
biological source rabbit
clone polyclonal
concentration ~1 
concentricity mg/mL
connections o.d. unconjugated
Description ANTI-BCL-2
format buffered aqueous solution
glass tube l × o.d. × i.d. human ... BCL2(596)
MDM Code SAB4500003-100UG
Material Number SAB4500003
Business Unit 696
Shipping Mode COU
MRP Type YP
Local HS Code 30021500
Legacy SIGMA
Plant 6311
Sales Org 6304

Description

Application

Anti-BCL-2 antibody produced in rabbit has been used in western blotting.

Biochem/physiol Actions

BCL2 is an apoptosis regulator that is expressed in sub-cellular components such as the mitochondria and nucleus. While mitochondrial BCL2 inhibits apoptosis, BCL2 present in the nucleus may activate cell death. BCL2 may also regulate autophagy during starvation . Anti-BCL-2 antibodies are specific for endogenous levels of total BCL-2 protein in rats, humans and mice.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

B-cell lymphoma 2 (BCL-2) is an integral inner mitochondrial membrane protein that acts as an antiapoptotic protein. It is a target gene of nuclear factor kappa B (NF-kB). The gene encoding BCL-2 is localized on human chromosome 18q21.

Immunogen

The antiserum was produced against synthesized peptide derived from human BCL-2.

Immunogen Range: 46-95

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

SAFETY INFORMATION

Signal Word

RIDADRRIDADR

WGK Germany

nwg

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.