SMB00702
Sigma-Aldrich

APIGENIN,>=97% (TLC), FROM CITRUS

Empform:

C15H10O5

Synonyms English:

4′,5,7-Trihydroxyflavone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone

Nacres: NA.79
Mdl No: MFCD00006831
Fw: 270.24
CAS Number: 520-36-5
Grouped product items
SKU Pack Size Availability Price Quantity
SMB00702-5MG - Available to ship on April 02, 2024
IDR 878,000.00
SMB00702-100MG - Available to ship on April 02, 2024
IDR 7,944,000.00
SMB00702-25MG - Available to ship on April 02, 2024
IDR 2,557,000.00
Request a Bulk Order Check Availability

Properties

Properties
assay
assay range 97% (TLC)
Description APIGENIN,>=97% (TLC), FROM CITRUS
format powder
glass tube l × o.d. × i.d. human ... ADORA3(140) CDC2(983) CDK5(1020) CDK6(1021) CYP1A2(1544) ESR1(2099) ESR2(2100) GSK3A(2931)
mouse ... Hexa(15211)
rat ... Adora1(29290) Adora2a(25369) IL4(287287) Tnf(24835)
inchi key 1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-716-18H
indiff. to chromic acid KZNIFHPLKGYRTM-UHFFFAOYSA-N
MDM Code SMB00702-5MG
Material Number SMB00702
Business Unit 777
Shipping Mode AIR
MRP Type YP
Local HS Code 29329900
Legacy SIGMA
Plant 6311
Sales Org 6304
CAS Number 520-36-5

Description

Biochem/physiol Actions

A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

General description

Apigenin (ApI) is also called as 5,7,4′-trihydroxyflavone. It is a natural compound, found in several fruits and herbs, like, oranges, onions and parsley.

SAFETY INFORMATION

Signal Word

RIDADRRIDADR

WGK Germany

WGK 3

Flash Point (F)

Flash Point (C)

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

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