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    • APIGENIN,>=97% (TLC), FROM CITRUS

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    Documents SDS COO/COA Specification Sheet
    SMB00702
    Sigma-Aldrich

    APIGENIN,>=97% (TLC), FROM CITRUS

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    Empform:

    C15H10O5

    Synonyms English:

    4′,5,7-Trihydroxyflavone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone

    Nacres: NA.79
    Mdl No: MFCD00006831
    Fw: 270.24
    CAS Number: 520-36-5
    Grouped product items
    SKU Pack Size Availability Price Quantity
    SMB00702-5MG - Available to ship on October 21, 2023
    IDR878,000.00
    SMB00702-100MG - Available to ship on October 21, 2023
    IDR7,944,000.00
    SMB00702-25MG - Available to ship on October 21, 2023
    IDR2,557,000.00
    Request a Bulk Order Check Availability
    Documents SDS COO/COA Specification Sheet

    Properties

    Properties
    assay ≥
    assay range 97% (TLC)
    Description APIGENIN,>=97% (TLC), FROM CITRUS
    format powder
    glass tube l × o.d. × i.d. human ... ADORA3(140) CDC2(983) CDK5(1020) CDK6(1021) CYP1A2(1544) ESR1(2099) ESR2(2100) GSK3A(2931)
    mouse ... Hexa(15211)
    rat ... Adora1(29290) Adora2a(25369) IL4(287287) Tnf(24835)
    inchi key 1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-716-18H
    indiff. to chromic acid KZNIFHPLKGYRTM-UHFFFAOYSA-N
    MDM Code SMB00702-5MG
    Material Number SMB00702
    Business Unit 777
    Shipping Mode AIR
    MRP Type YP
    Local HS Code 29329900
    Legacy SIGMA
    Plant 6311
    Sales Org 6304
    CAS Number 520-36-5

    Description

    Biochem/physiol Actions

    A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

    General description

    Apigenin (ApI) is also called as 5,7,4′-trihydroxyflavone. It is a natural compound, found in several fruits and herbs, like, oranges, onions and parsley.

    SAFETY INFORMATION

    Signal Word

    RIDADRRIDADR

    WGK Germany

    WGK 3

    Flash Point (F)

    Flash Point (C)

    Target Organs

    Risk Statement

    Supplemental Hazard Statements

    DOCUMENTATION

    Certificate of Analysis View Sample COA
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    Certificate of Origin
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