[3:39 PM] Rifki Akbar
SRP6517
Sigma-Aldrich

ALPHA 2 HS GLYCOPROTEIN,HUMAN PLASMA

Synonyms English:

Alpha-2-Z-globulin

Nacres: NA.32
Grouped product items
SKU Pack Size Availability Price Quantity
SRP6517-1MG - Available to ship on May 02, 2024
IDR 5,318,000.00
Request a Bulk Order Check Availability

Properties

Properties
assay
assay range 90% (SDS-PAGE)
blade diam. human
Description ALPHA 2 HS GLYCOPROTEIN,HUMAN PLASMA
format lyophilized
glass tube l × o.d. × i.d. human ... AHSG(197)
MDM Code SRP6517-1MG
Material Number SRP6517
Business Unit 694
Shipping Mode AIR
MRP Type PD
Local HS Code 30021210
Legacy SIGMA
Plant 6311
Sales Org 6304

Description

Biochem/physiol Actions

AHSG (α2-HS glycoprotein) is a multifunctional protein, and acts as an inhibitor of insulin receptor tyrosine kinase. It is involved in insulin resistance by promoting adipose tissue inflammation by functioning as a ligand for Toll-like receptor 4. Therefore, it is linked to the type 2 diabetes. This protein plays a crucial role in the prevention of extracellular calcification. This protein is a candidate plasma biomarker for early hypopharyngeal squamous cell carcinoma (HSCC) diagnosis. It is also a negative acute-phase protein, and its serum levels reduce drastically following surgeries, trauma, burns, and severe inflammation. Studies in Chinese populations show the serum levels of this protein is linked with fatty liver index (FLI), alanine aminotransferance (ALT), and aspartate aminotransferance (AST), which are early indicators of nonalcoholic fatty liver disease (NAFLD).

General description

AHSG (α2-HS glycoprotein), or fetuin-A, is a predominant serum glycoprotein with a molecular weight of 64kDa, and is produced and secreted primarily by hepatic cells. It is highly present in the extracellular matrix (ECM) of the bone.

Physical form

Lyophilized from 20 mM Tris-HCl, pH 7.5, with 2 mM EDTA.

SAFETY INFORMATION

Signal Word

RIDADRRIDADR

WGK Germany

WGK 1

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

TECHNICAL SERVICE

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