[3:39 PM] Rifki Akbar
C4911
Sigma-Aldrich

CHLOROTHIAZIDE

Empform:

C7H6ClN3O4S2

Synonyms English:

6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

Nacres: NA.77
Mdl No: MFCD00058576
Fw: 295.72
Pubchem Substance Id: 24278150
CAS Number: 58-94-6
Grouped product items
SKU Pack Size Availability Price Quantity
C4911-50G - Available to ship on April 25, 2024
IDR 4,941,000.00
Request a Bulk Order Check Availability

Properties

Properties
assay
assay range 98% (HPLC)
blade diam. synthetic (organic)
Description CHLOROTHIAZIDE
format powder
glass tube l × o.d. × i.d. human ... CA1(759) CA4(762) SLC12A3(6559)
inchi key 1S/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(912)13)17(1415)11-3-10-5/h1-3H(H1011)(H291213)
indiff. to chromic acid JBMKAUGHUNFTOL-UHFFFAOYSA-N
MDM Code C4911-50G
Material Number C4911
Business Unit 760
Shipping Mode AIR
MRP Type YP
Local HS Code 29359000
Legacy SIGMA
Plant 6311
Sales Org 6304
CAS Number 58-94-6

Description

Application

Chlorothiazide has been used as a reference standard in parallel artificial membrane permeability assay (PAMPA). It has also been used to test its effect on blocking pendrin activity.

Biochem/physiol Actions

Chlorothiazide (CTLD) shows structural resemblance with hydrochlorothiazide by having a sulfonamide group, but exhibits a long action duration. CTLD is an inhibitor of carbonic anhydrase and is more potent than hydrochlorothiazide.

General description

Chlorothiazide (CTLD) is a thiazide-like diuretics 

Immunogen

and has antihypertensive effects.

SAFETY INFORMATION

Signal Word

Danger

P261 - P272 - P280 - P284 - P302 + P352 - P304 + P340 + P312

RIDADRRIDADR

WGK Germany

WGK 2

Flash Point (F)

Not applicable

Flash Point (C)

Not applicable

Target Organs

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

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